Abstract:

Retinal microaneurysm can appear in multiple fundus diseases.  It occurs mostly in the early stage of the disease, and its number often indicates the severity of the disease. Its mechanisms include changes in retinal hemodynamics, inflammatory mechanisms, oxidative stress and oxidative damage.  Optic coherence tomography angiography (OCTA) and adaptive optics scanning light ophthalmoscope-fluorescein angiography (AOSLO-FA) as a newly developed vascular imaging method may become a major development in the detection of retinal microaneurysm.